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ID:57
Study Name:MIDSECTION
Iras Number:303887
Study Type:Interventional
Anatomical Region:Abdomen
Disease Site:Abdomen
Study Status:Open
Site Location:
The Christie NHS Foundation Trust
Wilmslow Road, Manchester, M20 4BX
The Christie NHS Foundation Trust
Full Study Title:
A feasibility study of MRI Guided Stereotactic Ablative Radiotherapy to Abdomino-Thoracic Targets
Research Summary:

The MR‑Linac is an advanced type of radiotherapy machine. It combines radiotherapy with high‑quality MRI imaging, which means we can see the tumour more clearly during treatment. This may help us treat the cancer more accurately while protecting healthy tissues.

The MIDSECTION study is a research project looking at whether it is practical and comfortable for patients to receive a type of precise radiotherapy called SABR (stereotactic ablative body radiotherapy) using the MR‑Linac. This study focuses on tumours in the chest and abdomen, including both primary cancers and cancers that have spread (metastases).

What taking part involves

Patients whose cancer is in one of the areas being studied may be offered treatment on the MR‑Linac as part of this research. If you take part, you may also be invited to:

  • Have some extra MRI scans
  • Provide optional blood samples
  • Provide an optional stool (poo) sample

These extra tests are completely optional.

What the study is trying to find out

The main aim is to see:

  • Whether treating these tumours with MR‑guided SABR is feasible (practical to deliver)
  • Whether patients find this treatment tolerable and manageable

The study will help us understand how well the MR‑Linac works for cancers in the abdomen and chest, and whether it could improve accuracy and outcomes for future patients.

Contact Information:
If you have interest in this study, please discuss this with your oncology healthcare team.
Date Site Open:
AUG
29
2025
Study End Date:
JUL
01
2028
Randomisation
Additional Appointments
Link to NIHR Database: Not provided